Coherent Identifier About this item: 20.500.12592/djwz5x

A Quality Initiative of the Program in Evidence-Based Care (PEBC), Cancer Care Ontario (CCO)

2017

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Summary

Interpretation of Evidence for Recommendation 1 Despite the lack of comparison with pelvic MRI, which is considered the current standard in the diagnostic work-up of anal canal cancer, PET or PET/CT showed high sensitivity in visualizing the primary tumour and identifying involved lymph nodes as compared with CT. [...] Recommendation 2 There is insufficient evidence to recommend the use of PET or PET/CT in the assessment of treatment response. [...] Interpretation of Evidence for Recommendation 2 Owing to the small number of studies evaluating the role of PET or PET/CT in the assessment of response after chemoradiotherapy and the inconsistent timing of assessment, the evidence is currently insufficient to support the use of PET or PET/CT in this setting. [...] Interpretation of Evidence for Recommendation 3 Owing to small sample size as well as the lack of data on the frequency and timing of routine follow-up, the evidence is currently insufficient to support the use of PET or PET/CT in this setting. [...] The purpose of this report is to develop an evidentiary base to inform recommendations with respect to the role of PET or PET/CT in the staging, response evaluation, and follow-up of anal canal cancer.

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health lung cancer guideline research guidelines cancer medicine radiotherapy health care evidence-based medicine therapy clinical trial clinical medicine systematic review society healthcare policy health treatment health sciences government health care virus disease ct scan cancer staging positron emission tomography fdg-pet staging pet computed tomography

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