HIV transmission : Transmission du VIH : les facteurs qui affectent le risque biologique

The mucous membranes are vulnerable to infection because they lack the keratin layer, the epithelial cells are loosely packed, have fewer layers (just one layer in the case of the rectum and part of the cervix), have a high concentration of a certain kind of immune cell that HIV likes to infect (known as HIV target cells), and the tissues are much easier for HIV to penetrate. [...] Over a span of one to three days, many types of immune cross the cell layer or win its battle against the immune cells in cells in the mucous membranes attack HIV in an effort to rid the the tissue below. [...] The size of the and foreskin) is much smaller than the surface area of the rectum surface area of mucosal membranes that are in contact is one. [...] As described The analysis, based on the results of four studies, estimated the risk in more detail in Section 2.6, Circumcision status, removal of the through receptive anal sex (receiving the penis into the anus, foreskin can decrease the risk of HIV infection because it reduces also known as “bottoming”) to be 1.4%. [...] Therefore, if someone has an STI in the mouth, with HIV, therefore the inflammatory response brings more HIV genitals or rectum, and that area is exposed to HIV, the higher (contained in the infected immune cells) to the site of the STI concentration of “activated” CD4 cells facilitates HIV infection, in the genitals or rectum.