As a result, the overall aim of this report is to evaluate the clinical efficacy and incremental cost-effectiveness of pioglitazone and rosiglitazone in the treatment of adults with type 2 diabetes. [...] Separate objectives are: 1. To review the published literature surrounding the clinical efficacy of rosiglitazone and pioglitazone, in terms of glycemic control, in the treatment of patients with type 2 diabetes; 2. To describe and quantify the effect of rosiglitazone and pioglitazone on glycemic control; 3. To estimate the long-term costs and consequences of rosiglitazone and pioglitazone in comp [...] Objectives The overall aim of this report is to evaluate the clinical efficacy and incremental cost-effectiveness of pioglitazone and rosiglitazone in the treatment of adults with type 2 diabetes. [...] The studies meeting predefined inclusion/exclusion criteria were then used to fulfill two purposes for this section of the health technology assessment report: 1) to qualitatively describe the existing published literature on the efficacy of rosiglitazone and pioglitazone in the treatment of type 2 diabetes mellitus; and 2) to use meta-analytic techniques to quantitatively summarize the efficacy o [...] This search allowed for the determination of the potential size of the literature base and clarified the search terms to be used in the complete search.
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