Optimal treatment strategies for localized Ewing's sarcoma of bone after neoadjuvant chemotherapy /

The outcomes valued by the clinicians in this guideline will align with the outcomes valued by the patient and most patients will view these recommendations as acceptable; the interpretation of the evidence will align with the interpretation of most clinicians in Ontario and the recommendations will Section 2: Guideline – December 22, 2015 Page 5 Guideline 11-6 probably be accepted by most provide [...] The PEBC has a formal standardized process to ensure the currency of each document, through the periodic review and evaluation of the scientific literature and, where appropriate, the integration of that literature with the original guideline information. [...] The project was led by a small working committee of the group, referred to as the Working Group from this point forward, whose members were responsible for creating the evidence base, drafting the first version of the recommendations and leading the response to the external review. [...] The Working Group members are noted in Appendix 1. All the Sarcoma Section 3: Guideline Methods Overview – December 22, 2015 Page 7 Guideline 11-6 DSG members contributed to the final interpretation of the evidence, refinement of the recommendations, and approval of the final version of the document. [...] To achieve approval of the draft document and final document, a consensus of 75% of the members of the Sarcoma DSG was required, with dissenting opinions noted, where appropriate.