2019 Evidence Update

The strength of the body of evidence increases with the quality of the systematic reviews included in the analysis, the number of unique primary research studies included within the reviews, and the consistency of the findings. [...] HBOT has been shown to be clinically-effective in the treatment of delayed radiation-induced injuries of the head and neck and of the pelvic regions by improving wound healing and quality of life. [...] The benefits of HBOT for wound healing will depend on the severity of the injury and on the timeliness of treatment. [...] More research is needed to determine the effectiveness of HBOT for healing a variety of wounds and decision makers can expect future studies to have an impact on the body of evidence for the effectiveness of HBOT to treat conditions for which there is insufficient evidence at present. [...] Weak Positive effect Table 3: Evidence for clinical effectiveness of HBOT for wound size reduction in diabetic foot ulcers New for this update: HBOT for other outcomes in diabetic pressure ulcers The systematic reviews included in this update reported on other outcomes for diabetic pressure ulcers that are not found in the original report.