Contact Charlene E. Le Beau: clebeau@jccf.ca

To acquiesce to the mandate by submitting to it implies his support of the mandate and of this vaccine. [...] To support the government and employer pressure to be vaccinated or lose one’s job is a violation of this liberty and the denial of God‘s presence in his life. [...] Molnupiravir 800mg PO BID x 5 days is not routinely recommended (if/once available in Canada); if used on a case-by-case basis in patients who are unable to receive nirmatrelvir/ritonavir, sotrovimab or remdesivir, the uncertainty of benefit and the absolute risk of hospitalization, including factors such as age, number and type of co-morbidities and severity of symptoms need to be considered. [...] In evaluating the primary outcome of Covid-19–related hospitalization or death from any cause, 2 of 279 patients (0.7%) in the remdesivir group and in 15/283 (5.3%) in the placebo group met the primary endpoint, p=0.008. [...] Patients in this priority tier have a hospitalization rate between 15-20% according to data from December 2021 and January 2022; mitigating this level of risk is beneficial to the individuals and maximizes the health benefits to the population as per the Ethical Framework for Allocating Scarce Drug Therapies.