Anterior uveitis and diffuse scleritis after pamidronate infusion

20.500.12592/xgxd6z5

Anterior uveitis and diffuse scleritis after pamidronate infusion

7 Dec 2023

She pre- sented to an emergency eye clinic 6 days later and had a visual acuity of 20/30 in the left eye and only light perception in Figure 1: A) Pamidronate-induced anterior uveitis and diffuse scleritis in a 58-year-old woman. [...] B) A computed tomography scan of the orbits showed right-sided proptosis and tion deficit, corneal edema and a hypo- circumferential scleral thickening and hypervascularity with adjacent edema (green arrow), consistent pyon (Figure 1A). [...] uveitis is managed empirically with topical corticosteroids She was treated empirically with topical moxifloxacin, cortico- and antibiotics with close follow-up by an ophthalmologist.3 steroids and cycloplegics. [...] Postmarketing surveillance rates of uveitis and scleritis We saw the patient a week later and diagnosed drug-induced with bisphosphonates among a national veteran cohort. [...] Drug-induced Content licence: This is an Open Access article distributed in accordance uveitis or scleritis may be seen with use of parenteral or oral with the terms of the Creative Commons Attribution (CC BY-NC-ND 4.0) bisphosphonates, with incidence rates of 7–114 per 10 000 and licence, which permits use, distribution and reproduction in any medium, 8–63 per 10 000 people per year, respectively.
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