Down syndrome and Alzheimer’s disease - What is Alzheimer’s disease? What is Down syndrome?

2 Down syndrome and Alzheimer’s disease What are some of the warning signs of dementia in a person that has Down syndrome? The first sign of dementia in individuals with Down syndrome is often changes in their behaviour and personality (Ball et. [...] How is Down syndrome associated with Alzheimer’s disease5? The hallmarks of Alzheimer’s disease are the presence of “plaques” and “tangles” in the brain. [...] As with the general population, the chances of those with Down syndrome developing the plaques and tangles characteristic of Alzheimer’s disease increase with age. [...] However, it is important to note the differences in the progression of the disease for individuals with Down syndrome. [...] 9 The Alzheimer Society of Canada developed the Progression series, a five-part series on the stages of Alzheimer’s disease, which is written for the person with the disease, their family and caregivers.