After a re-evaluation of the antimicrobial active ingredient sodium omadine, Health Canada’s Pest Management Regulatory Agency (PMRA), under the authority of the Pest Control Products Act and Regulations, is proposing continued registration of products containing sodium omadine for sale and use in Canada. [...] The Overview describes the regulatory process and key points of the evaluation, while the Science Evaluation provides detailed technical information on the assessment of sodium omadine. [...] The PMRA will then publish a Re-evaluation Decision2 that will include the decision, the reasons for it, a summary of comments received on the proposed decision and the PMRA’s response to these comments. [...] Following the re-evaluation announcement for sodium omadine, the registrant of the technical grade active ingredient in Canada indicated their intention to support all currently registered uses, except for the use of sodium omadine in the preservation of aqueous synthetic fibre lubricants (spin finishes) and for “dry-film” preservation of latex-based emulsions. [...] With respect to the completeness of the toxicity database as it pertains to the toxicity to infants and children, the database for sodium omadine contains the full complement of required studies, including developmental toxicity studies in rats and rabbits and a two-generation reproductive toxicity study in rats.