The key objective of the Pest Control Products Act is to prevent unacceptable risks to people and the environment from the use of pest control products. [...] These methods and policies also consider the nature of the effects observed and the uncertainties when predicting the impact of pesticides. [...] Taking into consideration these label statements, the number of applications and the expectation of the exposure period for handlers and workers, the health risk to these individuals are not expected to be of concern. [...] The scientific quality of the data is acceptable, and the database is considered adequate to characterize the toxicity of propoxycarbazone-sodium. [...] Analysis of the metabolites indicated that only a small number of minor metabolites, each accounting for less than 3% of the AD, were detected in the urine and feces, with the exception of a fecal metabolite which accounted for 2-9% of the AD.