Left ventricular assist devices for destination therapy

Objectives Our objectives were to: Determine the clinical effectiveness of LVADs for destination therapy for patients with end-stage heart failure who are ineligible for heart transplantation Estimate the cost-effectiveness of destination-therapy LVAD for patients with end-stage heart failure who are ineligible for heart transplantation and to estimate the potential budget impact for the Ontar [...] What is the potential budget impact over the next 5 years for the Ontario Ministry of Health and Long-Term Care of LVADs for destination therapy in end-stage heart failure patients who are ineligible for heart transplantation? [...] Nevertheless, the included cost-utility studies considered similar comparators, settings/perspectives, and treatment regimens: the study conducted in the Netherlands closely mimicked the Ontario context, and the studies conducted in the United States closely aligned with the treatment regimens and comparators in Canada. [...] February 2016 BUDGET IMPACT ANALYSIS We conducted a budget impact analysis from the perspective of the Ontario Ministry of Health and Long-Term Care to estimate the cost burden of LVAD for destination therapy in 2015 and over the following 4 years (2016 to 2019) under the assumption of limited diffusion. [...] Objective The objective of this analysis was to determine the budget impact for the Ontario Ministry of Health and Long-Term Care of LVADs for destination therapy in end-stage heart failure patients who are ineligible for heart transplantation.