Now is the time to make sure that the post-diagnostic care pathway is optimised to the person needs and that the healthcare systems in each country are properly harnessed and informed to provide the most appropriate treatments to the right patient at the right time. [...] 24 ANTICIPATED PATHWAY TRANSFORMATIONS WITH INNOVATIVE TREATMENTS A Holistic and Personalised Approach As a multitude of different complementary AD treatments and interventions will become available, future management and care of AD will need to focus on effectively integrating these different approaches with the aim to increase the quality of life of the person living with AD and its environment. [...] Gap 3 ‒ Lack of Alzheimer’s disease-specific focus • Lack of awareness and knowledge of AD (how it is different from other forms of dementia, as well as the misconception that it is a part of natural ageing) and the existing treatment options among the general public and within the community of healthcare professionals. [...] • Foster and support educational and awareness campaigns in society and among HCPs at national and EU level about early detection of AD, access to diagnostic centres, and the benefits of the post-diagnostic care across the EU through existing funding and educational mechanisms. [...] From 2021 onwards, she has been a member of the management group in the scientific panel for dementia and cognitive disorders of the European Academy of Neurology, and from 2022 she has been the co-chair in the same panel.
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Table of Contents
- TABLE OF CONTENTS 3
- EXECUTIVE SUMMARY 5
- FOREWORD 6
- CALL TO ACTION POLICY RECOMMENDATIONS 8
- RECOMMENDATIONS 9
- Recommendation 1 9
- Recommendation 2 9
- Recommendation 3 9
- Recommendation 4 9
- Recommendation 5 9
- Recommendation 6 9
- Recommendation 7 9
- Recommendation 8 9
- LIST OF ENDORSERS 10
- INTRODUCTION 12
- The window of opportunities Mild Cognitive Impairment 14
- RETHINKING ALZHEIMERS DISEASE PHASE I MAPPING THE DETECTION AND DIAGNOSTIC JOURNEY 15
- Alzheimers Disease Biomarkers 16
- Biomarker Detection and Diagnosis open the way to early prevention and treatment 17
- Current Pharmacological Treatment Options 18
- Other Non-Pharmacological Approaches 19
- Social Care Services 20
- PIONEERING HORIZONS INNOVATIVE TREATMENTS FOR ALZHEIMERS DISEASE 21
- Pharmacological Therapies 22
- Gene-Therapy 23
- Neuromodulation 23
- ANTICIPATED PATHWAY TRANSFORMATIONS WITH INNOVATIVE TREATMENTS 24
- Treatment Means Time 24
- No Disease for Old Men 24
- A Holistic and Personalised Approach 25
- Brain Capital Gain 25
- UNVEILING CURRENT GAPS AND CHALLENGES IN THE POST- DIAGNOSTIC CARE PATHWAY FOR ALZHEIMERS DISEASE 26
- Current Gaps 26
- Challenges with New Treatments 27
- CALL TO ACTION POLICY RECOMMENDATIONS 29
- CONCLUSION 33
- ACKNOWLEDGMENTS 35
- AUTHORS EXPERTS BIOGRAPHIES 36
- REFERENCES 40
