COVID-19 Vaccine Development Landscape NACI Presenters: April Killikelly and Matthew Tunis August 13, 2020

COVID-19 Vaccine Development Landscape NACI Presenters: April Killikelly and Matthew Tunis August 13, 2020 Information for Health Care Providers on Allergies and Anaphylaxis following administration of COVID-19 vaccines Presenters: Bryna Warshawsky and Catherine Dickson Q and A: Joseline Zafack February 10, 2021 Conflicts of interest • Bryna Warshawsky – no conflicts of interest to declare • Cathe. [...] • Does not include data from Quebec • Cases of anaphylaxis were identified using all ICD-10CA codes related to anaphylaxis 11 Anaphylaxis following Pfizer-BioNTech COVID-19 vaccine • One case of anaphylaxis in clinical trials • US: 50 cases of anaphylaxis (5.0 per million doses administered)* • Interval between vaccination and onset of symptoms*: – 74% within 15 minutes – 16% within 15 to 30 minut. [...] anaphylaxis) to injectable therapy not related to a component of a COVID-19 vaccine - do not need to be assessed - 30 minutes of observation post-vaccination Subject to change 19 Not a contraindication nor a precaution Individuals with a history of allergy not related to a component of a COVID-19 vaccine or other injectable therapy (e.g. [...] 22 Fainting • Cause: – Anxiety, stress or pain leads to low pulse and blood pressure and subsequent lack of blood flow to the brain • Prevention: – Ask clients if they have ever fainted during or after a vaccine or medical procedure – Observe for signs of being overly anxious, pale or sweating – If any of the above, vaccinate lying down • Management: – Lie down on back, turn on side if going to vo. [...] Transfer to hospital for observation 25 Management of hives at the injection site • Itchy, swollen bumps at the injection site • Observe for 30 minutes to ensure the hives remain localized • Can apply ice to the i.