We quan system costs, COPD was associated among surgical patients, and patients tified the association of COPD with sur with a partially adjusted relative with COPD have higher risk for compli vival (Cox proportional hazards models) increase of 13.1% (95% CI 12.7%– cations and death within 30 days after and costs (linear regression model with 13.4%), and an increase of 4.6% (95% surgery. [...] 1 Patients with COPD are at term owing to age and other comorbidities.8,9 Understanding the increased risk for complications and death within 30 days longer term outcomes of surgical patients with COPD is critically after surgery;2–4 previous work estimates a 35% increase in important to accurately guide informed consent discussions and odds of morbidity and a 30% increase in odds of death attrib. [...] Patients with COPD had 13.1% (95% CI 12.7%–13.4%) higher Effect modification analysis total costs with partial adjustment and 4.6% (95% CI 4.3%–5.0%) We found evidence of significant interaction between COPD and higher total costs with full adjustment, which was similar to frailty, COPD and cancer, and COPD and procedure type (HRs for higher costs in the year after surgery (15.0% [95% CI 14.0%–. [...] Interpretation Patients with COPD typically have concurrent comorbidity, bio psychosocial issues and frailty.44 For example, 50% of patients with Patients with COPD had lower survival and greater health care COPD have a high burden of comorbidity, and almost 1 in 5 live with costs in the year after scheduled surgery than patients without frailty. [...] Parts of this material are University of Ottawa; Department of Anesthesi supported in part by a Merit Award from the based on data and information compiled and ology and Pain Medicine (McIsaac), The Ottawa Department of Anesthesiology and Pain Medi provided by the Canadian Institute for Health Hospital; Ottawa Hospital Research Institute cine at the University of Toronto, and by the Information.
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