(Because we covered (IPT) were included in our review, particularly given that IPT was identified as reducing this latter RCT in our Spring 2008 issue, we provide only the main depressive symptoms in children and youth highlights in the sidebar on page 11.) in our 2014 report Child and Youth Mental Disorders: Prevalence and Evidence-Based The ABCs of the CBT trials Interventions.10 Although we did. [...] and II), the medication failed to outperform placebo on either of the two symptom measures.21–22 However, the three other RCTs (fluoxetine III through V) did show significant benefits on one to four symptom measures.16, 23–24 Two of the successful fluoxetine RCTs also assessed the clinical importance of the symptom reductions. [...] (These outcomes build on our previous review of a fluoxetine study, also highlighted in the sidebar, showing that depression symptoms improved for the majority of adolescents on the medication.) Our current review also found evidence supporting the use of the medications clomipramine and escitalopram, according to one RCT each. [...] Journal Two-year outcome of children treated for of the American Academy of Child and Adolescent depression. [...] Journal of the American A double-blind efficacy and safety study of Academy of Child and Adolescent Psychiatry, 45, duloxetine fixed doses in children and adolescents 1404–1411.
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