The association of sensitivity and specificity with disease prevalence: analysis of 6909 studies of diagnostic test accuracy Research CPD The association of sensitivity and specificity with disease prevalence: analysis of 6909 studies of diagnostic test accuracy M. [...] We sought to evaluate the pared with the lowest quartile of showed that prevalence was positively association between prevalence and prevalence, the second, third and associated with sensitivity and nega- changes in sensitivity and specificity. [...] Leeflang and colleagues2 provided ity of a positive test given that the person has the target condition, 4 examples of individual diagnostic studies in which sensitivity and and the probability of a negative test given that the person does specificity changed as the prevalence changed, and Li and Fine3 not have the condition, respectively.1 In practice, sensitivity and showed the same in 2 meta-an. [...] Brenner and Gefeller9 evaluated the coefficients of prevalence from bivariate regression models effect of a hypothetical continuous trait that categorizes people showed the direction and strength of the association between into diseased and not diseased, and found that the dependence prevalence and sensitivity and specificity. [...] Other causes of variability include the strin- nostic tests are associated with the prevalence of the target con- gency or misclassification of the gold-standard test or the threshold dition.
- Pages
- 7
- Published in
- Canada
