The combination of of research into the heritability of cancer. [...] The mutilating nature of early mastec- these factors, alongside highly public rep- The BRCA1 sequence variation was iso- tomies as a treatment for breast cancer resentations of risk-reducing mastec- lated in 1994, with BRCA2 isolated a year and the high stakes for femininity, sexual- tomies, not only introduced the proced- later. [...] A testing and screening.5 A great deal of this variant, increased regular screening was bilateral risk-reducing mastectomy is 1 of is owing to the so-called Angelina effect, the first and most obvious step, alongside several treatment options and, in many namely the rise in awareness spearheaded highly sensitive magnetic resonance ways, the most radical; recent representa- by Angelina Jolie’s 2013. [...] The advocacy efforts are part of shifting approach to risk-reducing analysis of 7195 women at high-risk of breast the story. [...] Risk-reducing mastectomy rates in the US: a closer examina- To highlight the differences in attitude not only patient attitudes but the meaning tion of the Angelina Jolie effect.
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