Appendix 2 Table of Contents

Different foci and perspectives can also lead to differences in recommendations; for example, the CTFPHC that focuses on preventive care has a different Hepatitis C screening recommendation than the Canadian Association for the Study of the Liver that provides guidance on the management of Hepatitis C that included a recommendation about screening. [...] We excluded breast cancer screening and prostate cancer, that are covered by the CTFPHC and the USPSTF, after we considered the effectiveness of screening and the likelihood that equitable preventive care could promote equitable health outcomes and we point to the need for more research. [...] Based on the disparities in colorectal cancer outcomes and in screening uptake and the effectiveness of screening, we decided it is reasonable to start outreach for colorectal cancer screening at age 45 years on the understanding that there may be a delay between the initiation of screening outreach and the actual start of screening. [...] HIV and Hepatitis C Our recommendation for age-based Hepatitis C screening is the same as the recommendation from the USPSTF, but differs from the CTFPHC recommendation for risk-factor based screening. [...] The recommendations for age-based screening from the USPSTF and the Canadian Association for the Study of the Liver are based on the prevalence of Hepatitis C and the effectiveness of treatment.