Benzodiazepines
Benzodiazepines (BZD, BDZ, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which, since 1963, has also marketed the benzodiazepine diazepam (Valium). In 1977 benzodiazepines were globally the most prescribed medications. They are in the family of drugs commonly known as minor tranquilizers.Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic …
WikipediaPublications
CCSA: Canadian Centre on Substance Use and Addiction · 20 March 2024 French
Le présent guide s’adresse aux personnes vivant au Canada qui songent à suivre un programme de traitement avec hébergement pour l’usage de substances.
certaines substances comme les opioïdes, les benzodiazépines et l’alcool. Cela peut entraîner de graves … thérapie par agonistes contrôlées (p. ex. benzodiazépines ou stimulants), il est important opioïdes consiste …
Office of the Auditor General of British Columbia · 14 March 2024 English
Two key approaches to harm reduction are (1) supervised consumption and overdose prevention services, and (2) increased access to prescribed safer supply. The two audits here looked at whether the …
introduction of benzodiazepines into the unregulated drug supply chain. Benzodiazepines made drug toxicity … to respond to toxic drug events involving benzodiazepines. At the time of the audit, the BCCDC was working … includes non-opioid drugs such as stimulants and benzodiazepines. • RMG prescribing continues and is understood …
CCSA: Canadian Centre on Substance Use and Addiction · 6 March 2024 English
Provides a comprehensive review of the Drug Checking Symposium 2023, emphasizing the importance of drug checking in promoting safety and awareness in the unregulated drug supply. Offers a comprehensive overview …
specific substance in a sample) for fentanyl, benzodiazepines and xylazine; Fourier-transform infrared (FTIR) …
CCSA: Canadian Centre on Substance Use and Addiction · 29 February 2024
Looks at how specific patterns of substance use may increase suicide risk. Highlights intersecting factors, such as the type of substance and the amount consumed, as well as biological and …
2011). Some prescription substances such as benzodiazepines are also associated with an increased risk … attempt and death by suicide (Dodds, 2017). Benzodiazepines are a sedative medication commonly prescribed … showed that the link between prescribed use of benzodiazepines and suicide attempts and death by suicide is … increases with the use of higher doses of benzodiazepines (dose–dependent effect) and is particularly … circumstances. • Prescribed medications such as benzodiazepines that might increase the risk of suicidal thoughts …
CCSA: Canadian Centre on Substance Use and Addiction · 29 February 2024
Examine comment certaines habitudes d’usage de substances peuvent augmenter le risque de suicide. Met en évidence des facteurs croisés comme le type de substance et la quantité consommée, ainsi que …
Certaines substances sur ordonnance comme les benzodiazépines, des sédatifs couramment prescrits contre l’anxiété … confirmé que la corrélation entre l’usage de benzodiazépines sur ordonnance et les tentatives et décès par … Certains médicaments sur ordonnance comme les benzodiazépines peuvent, seuls ou en combinaison avec d’autres … 1371/journal.pone.0126870 Dodds, T.J. « Prescribed benzodiazepines and suicide risk: A review of the literature …
Health and Welfare Commissioner of Quebec · 26 February 2024 French
Méthodologie
de la La posologie et l’intervalle entre de benzodiazépines vaccination contre les prises d’un médicament …
CMA: Canadian Medical Association · 14 February 2024 English
doi: 10.1503/cmaj.230378 Eosinophilic esophagitis is a chronic condition, which can affect both children and adults and encompasses a spectrum of disor- Key points ders; it is a common cause of …
mine, calcium-channel blockers, nitrates and benzodiazepines were meta-analysis had wide heterogeneity (I2 …
CCSA: Canadian Centre on Substance Use and Addiction · 12 February 2024
Provides information on frequently asked questions about in-patient treatment programs (also known as bed-based or residential programs). This guide explains what a person thinking about in-patient treatment for a substance …
stop using certain substances like opioids, benzodiazepines, and alcohol. Someone who has done this could … Opioid agonist treatment (OAT) (for example, benzodiazepines, stimulants), it is important that they involves …
CDPC: Canadian Drug Policy Coalition · 8 February 2024 English
Directly advocate at the provincial level for the federal government to fully repeal Section 4 of the Controlled Drugs and Substances Act and Section 8 of the Cannabis Act and …
those currently excluded such as ketamine and benzodiazepines to remove police to the greatest degree possible …
ODPRN: Ontario Drug Policy Research Network · 5 February 2024 English
3 Source: Office of Chief Coroner (OCC) - Data effective February 5, 2024 Includes confirmed and probable opioid toxicity deaths and ongoing investigations where information may be pending. [...] Number …
12.3 11.7 Benzodiazepines 0 0 0 4.1 10.9 28.7 Detection of nonpharmaceutical benzodiazepines* 32.7 29 … toxic levels of nitazenes, non-pharmaceutical benzodiazepines, and xylazine, these substances may not be … toxic levels of nitazenes, non-pharmaceutical benzodiazepines, and xylazine, these substances may not be … Alcohol Benzodiazepines Detection of Detection of xylazine* nonpharmaceutical benzodiazepines* 2018 2019 … 2019 2020 2021 2022 2023 (Q1 - Q3) Benzodiazepines are involved in over 3 in 5 opioid toxicity deaths …
