There has been a significant decrease in the morbidity and mortality of HIV-positive individuals in the province of British Columbia since the introduction of potent antiretroviral treatment in 1996. At present, there are approximately 13,000 HIV-positive individuals in the province, of which approximately only 5,400 are receiving antiretrovirals. In response to the need to expand the treatment of HIV-positive individuals and requests from the larger community of primary care providers, the British Columbia Centre for Excellence in HIV/AIDS (BCCfE) has developed guidelines to support care and treatment programs for people living with HIV.